Infertility

Infertility is a condition when the female partner is unable to get pregnant, despite multiple attempts. In the US alone, around ten to fifteen percent of couples are known to be infertile.

Infertility may be due to an issue with either you or your partner, or it could also be due to a combination of factors that are preventing pregnancy. However, there are several safe as well as effective therapies that are able to improve your or your partner’s chances of getting pregnant.

Symptoms

Pregnancy not occurring is the main symptom of infertility. Although there are generally no other obvious symptoms, a woman suffering from this condition might have irregular or absent menstrual periods. Men suffering from infertility might also show a few signs such as hormonal problems, changes in hair growth as well as sexual function.

In most cases, couples are able to conceive without any treatment.

For women, you should consider seeing a doctor about infertility issues if you have been unsuccessfully trying to get pregnant for over a year. You might consider seeing your doctor earlier if you:

  • Are age 35 or older and have been trying to conceive for six months or longer
  • Are over the age of 40
  • Have very painful periods
  • Have known fertility problems
  • Have irregular or absent periods
  • Have been diagnosed with conditions such as endometriosis or pelvic inflammatory disease
  • Have undergone treatment for cancer
  • Have had multiple miscarriages

 

For men, you should consider seeing a doctor if you have or experience:

  • A low sperm count or any other problems with sperm
  • A history of testicular, prostate, or sexual problems
  • Other members of your family having infertility problems
  • Having undergone treatment for cancer
  • Small testicles or swelling in your scrotum

Causes of Male Infertility

Generally speaking, in men, infertility is related to the following:

  • Effective production of sperm
  • Sperm count, or the number of sperm
  • Sperm shape
  • Movement of the sperm

 

There are a variety of risk factors as well, related to infertility in men, which include:

  • Older age
  • Obesity
  • Smoking Cigarettes
  • Excessive use of alcohol
  • Exposure to toxins such as heavy metals, pesticides, and herbicides

 

Few medical conditions also exist, that can cause male infertility. They include:

  • Retrograde ejaculation
  • Varicocele, or the veins around your testicles swelling
  • Testicles that haven’t descended into your scrotum
  • Having antibodies that attack your sperm, eventually destroying them
  • A hormonal imbalance, such as low production of testosterone

 

Various medications and drugs are also there, which lead to male fertility. They include:

  • Chemotherapy or radiation therapy, which are cancer treatments
  • Medication which is used for rheumatoid arthritis (RA) or ulcerative colitis (UC)
  • Recreational drugs like marijuana and cocaine
  • Anabolic steroids, which can help in improved athletic performance or hormonal issues like delayed puberty
  • Calcium channel blockers used for high blood pressure
  • Tricyclic antidepressants

Causes of Female Infertility

Various factors can lead to female infertility, which can affect or interfere with the following biological processes:

  • Ovulation, which occurs when the mature egg is released from the ovary
  • Fertilization, which occurs when the sperm meets the egg in the fallopian tube after it has traveled through the cervix and uterus
  • Implantation, which occurs after a fertilized egg attaches to the lining of the uterus where it is then able to grow as well as develop into a baby
    Some of the risk factors for female infertility include:
  • Increasing age
  • Excessive use of alcohol
  • Smoking cigarettes
  • Being obese, overweight, or significantly underweight
  • Sexually transmitted infections

 

There are also a variety of medical conditions which can lead to infertility, such as:

  • Ovulation disorders, which may be caused by hormonal imbalances or polycystic ovary syndrome (PCOS), or pelvic inflammatory disease
  • Endometriosis
  • Uterine fibroids
  • Premature ovarian failure
  • Scarring caused by a previous surgery

 

There are also certain medications as well as drugs which can affect female infertility such as:

  • Chemotherapy or radiation therapy
  • Antipsychotic medications
  • Using high-dosage non-steroidal anti-inflammatory drugs for long-term
  • Recreational drugs like cocaine and marijuana

Diagnosis

Before testing for infertility, your doctor or healthcare provider is going to work to understand your sexual habits, and might also make recommendations to help to improve chances of pregnancy. In some infertile couples, sometimes, infertility is unexplained.

It is important to note that evaluation for infertility can be expensive, and sometimes can involve procedures that are uncomfortable. There is also no guarantee that after all the testing and treatment, pregnancy is going to occur.

Tests for men

In order for a man to be fertile, it is important for the testicles to produce healthy sperm, and that the sperm is ejaculated effectively into the vagina, and then travel to the egg. Tests for male infertility generally attempt to determine if any of these processes are impaired.

Some of the tests can include semen analysis, genetic testing, hormone testing, testicular biopsy, imaging as well as any other testing.

Tests for women

For women, fertility relies on the ovaries releasing eggs that are healthy. The reproductive tract must allow the egg to pass into the fallopian tubes, and then join with the sperm, so that the fertilization can take place. Your doctor can recommend a general physical exam, as well as few other tests such as ovulation testing, ovarian reserve testing, imaging tests, etc.

Treatments

If despite multiple attempts, a couple is unable to achieve pregnancy, then treatment is an option. The type of treatment that your doctor might recommend might depend on a variety of factors, such as:

  • The cause of infertility, if known
  • The overall health of you as well as your partner
  • How long you’ve been trying to conceive
  • Age

For Men

Male infertility is treatable in various ways, depending on the cause. Generally, surgery, medication and assisted reproductive technology are the main treatment options.

Medications

Medications are used to treat issues like hormonal imbalances. They may also be used to treat a few other conditions that affect fertility in men, such as erectile dysfunction or any infections that can impact sperm count.

Surgery

Surgery helps to fix obstructions that prevent sperm from being present in the ejaculation. It might also help in correcting medical conditions such as varicocele. Sometimes, sperm is retrieved from the testicles directly, after which it is used in treatments with assisted reproductive technology.

Assisted reproductive technology

Assisted reproductive technology generally refers to treatments in which eggs and sperm and handled outside the body. It includes treatments such as in vitro fertilization (IVF), sperm injection, or intracytoplasmic sperm.

For Women

Although surgery can be used to treat female infertility as well, it has become quite rare now due to advancements in other fertility treatments. Surgery can improve fertility by:

  • Correcting an abnormally shaped uterus
  • Removing fibroids
  • Unblocking fallopian tubes

Reproductive assistance

Reproductive assistance involves methods such as intrauterine insemination and assisted reproductive technology. Intrauterine insemination involves injecting millions of sperm into a woman’s uterus near the time of ovulation.

IVF

IVF is one type of assisted reproductive technology that involves the removal of eggs which are then fertilized with a man’s sperm in the laboratory. After fertilization, the embryo can be placed back into the uterus.

Medications

Medications that are used to treat female infertility can work like hormones that are present naturally in the body to encourage or regulate ovulation.

Prevention

Having regular intercourse several times around the ovulation time can increase the chances of pregnancy. It is also noteworthy that all types of infertility are not preventable.

For men, it is important to avoid using too much tobacco, alcohol, or any such drugs, as well as any medications that can impact fertility. It Is also advisable to avoid high temperatures in hot tubs and hot baths, as well as avoid exposure to any kind of industrial or environmental toxins. Regular exercise can also help in improving sperm quality.

For women, it is important to quit smoking, reduce or stop the intake of alcohol, and also limit caffeine. Regular exercise is also important and can prove to be extremely beneficial.