Best Doctors in India for Amyloidosis Treatment

Best Hospitals in India for Amyloidosis Treatment

Hospital Highlights:

  • Fortis Hiranandani hospital was established in 2007.
  • The hospital is an advanced tertiary care, multi-specialty hospital equipped with 149 beds.
  • The hospital is equipped with a super ICU to provide emergency medical care to critically ill patients.
  • The hospital is NABH accredited.
  • The critical care facility in the hospital is augmented with the state-of-the-art facilities that facilitate speedier diagnosis and efficient monitoring.
  • The hospital provides specialty medical services in cardiology, orthopedic science, pediatric science, neurology, diabetic care, urology, nephrology, ENT, obstetrics, gynecology, cosmetic surgery, bariatric surgery, neuro and spine care.

Hospital Highlights:

  • W Pratiksha Hospital, Gurugram, is one of the best hospitals in the NCR region. It is also a top hospital in India for IVF. Since its inception, the hospital has performed over 5500 successful IVFs. The hospital also specializes in gynecology.
  • With over 20 years of experience in providing quality healthcare, the hospital is known as one of the most trusted and valued health providers in India.
  • Equipped with world-class medical facilities and advanced technology, the hospital’s doctors and clinicians also have a track record of delivering excellent results. The hospital is also known for focusing on preventive well-being as much as on curative treatment.
  • The hospital has earned the trust of its patients, by providing the best available treatments at affordable costs.

Hospital Highlights:

  • Paras hospital was established in 2006 and is the 250 bedded flagship hospital of Paras Healthcare.
  • The is supported by a team of doctors of international and national repute.
  • The hospital is NABH accredited and also the first hospital in the region to have a NABL accredited laboratory.
  • The hospital provides specialty medical services in around 55 departments including Neurosciences, Joint Replacement, Mother & Child Care, Minimal Invasive Surgery, Gynecology and Obstetrics, Ophthalmology, Dermatology, Endocrinology, Rheumatology, Cosmetic and Plastic surgery.
  • The hospital is equipped with state-of-the-art technologies.

Hospital Highlights:

  • Fortis Hospital, Anandapur, Kolkata is a world-class super-speciality equipped with the latest technologies in the medical world.
  • The hospital is NABH accredited.
  • This state-of-the-art facility specializes in cardiology and cardiac surgery, urology, nephrology, neurosciences, orthopaedics, digestive care, emergency care and critical care.
  • The hospital, governed by integrated Building Management System (IBMS), has a pneumatic chute system, for quick vertical and horizontal transportation between floors, facilitating speedy transfer of patient specimens, documents, reports, and medicines to the concerned departments.
  • The hospital also has a nephrology department with over 28 advanced dialysis units.

Hospital Highlights:

  • SL Raheja hospital is a 140-bed multi-specialty tertiary care hospital that is being managed by Fortis Healthcare Ltd.
  • The hospital is a benchmark in healthcare and medical facilities in the neighborhood of Mahim & the western suburbs.
  • L.Raheja Hospital, Mahim has one of the most effective ICU and Casualty care services.
  • The hospital provides specialty medical services in Cardiology, Oncology, Neurology, Orthopedics, Mother & Child Care, and in Diabetes.

Hospital Highlights:

  • Wockhardt Hospitals were established in the year 1973, originally called First Hospitals and Heart Institute.
  • Wockhardt Hospitals are super specialty health care networks in India, nurtured by Wockhardt Ltd, India’s 5th largest Pharmaceutical and Healthcare company.
  • Wockhardt Hospitals is associated with Partners Harvard Medical International, an international arm of Harvard Medical School, USA.
  • Wockhardt Heart Hospital performed India’s first endoscopic heart surgery.
  • The hospital has a state-of-the-art infrastructure equipped with the latest technologies and modern equipment.
  • It has special Centers of Excellence dedicated to the major specialties to provide hassle-free and high-quality clinical care.

Hospital Highlights:

  • The CK Birla Hospital in Gurugram is a NABH-accredited multi-specialty hospital.
  • The hospital strives to increase the quality of healthcare by focusing on UK NHS nurse and midwife training requirements. Policies and practices derived from the National Institute for Health and Treatment Excellence (NICE) recommendations in the United Kingdom ensuring that a strong focus on safety, high-quality clinical care, and sanitation is maintained.
  • The hospital’s cutting-edge technology and facilities allow for real-time communication and seamless collaboration among caregivers, ensuring accuracy and the best possible results. Those with foreign experience and accreditations make up part of the hospital’s team of clinicians.

Hospital Highlights:

  • As a member of the Apollo Hospitals Group, Apollo Hospitals International Limited, Ahmedabad is one of the most popular and sought-after medical facilities in Gujarat.
  • Through its 6 Centres of Excellence and various affiliated branches, which cover all specialties and subspecialties, the hospital provides the most advanced clinical services.
  • Since its inception in 2003, the hospital has been providing each patient with the most up-to-date medical equipment and state-of-the-art technology.
  • With more than 150 successful organ transplants, including liver and renal transplants, the facility has been able to build a strong and extensive organ transplant program.
  • In addition to performing 600 surgeries and caring for over 1800 patients on an IP basis, the hospital sees more than 18,000 patients on average in the outpatient department.
  • With one of the biggest cardiology teams in the area, the hospital provides state-of-the-art regional care treatment in Cardiac Sciences.
  • Additionally, the hospital offers a broad range of Neuro Interventional techniques to help stroke patients recover more quickly.

Hospital Highlights:

  • Jaypee Hospital is the flagship hospital of the Jaypee Group.
  • This hospital has commissioned 525 beds in the first phase and has been planned and designed as a 1200 bedded multi-specialty facility.
  • It holds the accreditation of the NABH and NABL.
  • The hospital has state-of-the-art infrastructure equipped with the latest technologies and modern equipment like 64 Slice PET CT, Dual Head 6 Slice SPECT CT, Gamma Camera, and Da Vinci Robotic Surgery for comprehensive robotic surgical solutions.
  • It has special Centers dedicated to the major specialties to provide hassle-free and high-quality clinical care.

Hospital Highlights:

  • Reliance Hospital is one of the best super-specialty care hospitals in Navi Mumbai.
  • The main purpose of this hospital is to become a trustworthy place for the best health and hope for society. The hospital is well connected to the suburbs of Mumbai and Navi Mumbai.
  • The hospital has various specialty departments, viz., Accident & Emergency, Anesthesiology, Dental Services, Dermatology, Diabetology, Dietetics Nutrition, Endocrinology, ENT, Gastroenterology, General Surgery, Gynaecology And Obstetrics, Hepato Pancreato Biliary Surgery, Infectious Disease, Internal Medicine, Interventional Radiology, Laboratory Medicine, Minimal Access Laparoscopic Surgery, Nephrology, Neurosciences, Opthalmology, Orthopaedics, Paediatrics, Pain Management Palliative Care, Physical Medicine Rehabilitation, Plastic And Reconstructive Surgery, Psychiatry, Pulmonary Medicine, Radiology, Rheumatology, Transplant, Urology Andrology, Vascular Surgery

AMYLOIDOSIS

Amyloidosis is a condition in which an abnormal protein known as amyloid builds up in your tissues and organs. It is a serious health issue, which can lead to even life-threatening organ failure.

Although amyloid is not found in the body normally, it can be formed from other different types of protein. Organs that are affected include the kidneys, heart, liver, spleen, nervous system as well as digestive tract. Some types of amyloidosis also occur as complications of other diseases, and these should improve with treatment of the underlying disease.

Symptoms

In many cases, symptoms are not noticeable till the condition is at an advanced stage. Signs and symptoms are going to depend on which part of your body is affected. Some of the symptoms may include any of the following:

  • Swelling of your ankles and legs
  • Severe weakness and fatigue
  • Unable to lie down in bed due to difficulty in breathing
  • Shortness of breath with minimal exertion
  • Tingling, numbness or pain in your hands or feet, especially in your wrist
  • Enlargement of the tongue
  • Unintentional weight loss of over 4-5 kilograms
  • Diarrhea, sometimes with blood or constipation
  • Irregular heartbeat
  • Difficulty swallowing
  • Skin changes, such as thickening or easy bruising

 

If you persistently experience any of the signs and symptoms, associated with amyloidosis, you should see your doctor.

Types, causes & risk factors

Many different proteins exist, which can lead to deposits of amyloid, though only a few have been linked to major health problems. The type of amyloidosis you have is determined by the type of protein and where it collects in your body. The deposits may collect throughout your body or in just one area.

The different types of amyloidosis include the following:

AL amyloidosis (immunoglobulin light chain amyloidosis) – This is the most common type of amyloidosis and therefore is also known as primary amyloidosis. AL stands for “amyloid light chains,” which is the type of protein that is responsible for this condition. The cause is unknown, but it occurs when your bone marrow makes abnormal antibodies that can’t be broken down. It’s linked with a blood cancer known as multiple myeloma. It can affect your kidneys, liver, heart, intestines, as well as nerves.

AA amyloidosis – Previously this condition was also known as secondary amyloidosis. It is caused by another chronic infectious or inflammatory disease which can be rheumatoid arthritis, ulcerative colitis, or Crohn’s disease. It mostly affects your kidneys, though in some cases, it may also affect your digestive tract, liver, or heart.

Dialysis-related amyloidosis (DRA) – This type is generally more common in older adults and people who have been on dialysis for over 5 years. This type of amyloidosis is caused by deposits of beta-2 microglobulin that build up in the blood. Deposits can build up in various tissues, though it most commonly affects the bones, joints, and tendons.

Hereditary amyloidosis – This is a rare form that is passed down through families. It is known to generally affect the liver, nerves, heart, as well as kidneys. There are also several other genetic defects that are linked to a higher chance of amyloid disease.

Age-related (senile) systemic amyloidosis – This is caused when there is a huge deposit of normal TTR in the heart and other tissues. It occurs mostly among older men.

Organ-specific amyloidosis – This is caused by deposits of amyloid protein in single organs, including the skin.

Some types of amyloid deposits have also been linked to Alzheimer’s disease, but the brain is rarely known to be affected by amyloidosis.

Amyloidosis is more common among men than in women. Your risk for amyloidosis generally goes up as your age increases. Amyloidosis also affects around fifteen percent of patients with a form of cancer which is called multiple myeloma.

Diagnosis

Sometimes, amyloidosis can get overlooked as the signs and symptoms can mimic those of more common diseases.

Early diagnosis can help to prevent further organ damage. However, a precise diagnosis is important as treatment is going to vary depending on your specific condition. Several tests can be required which include the following:

Blood and urine tests

Analyzing your blood or urine can indicate amyloidosis.

Biopsy

A tissue sample may be taken from the fat under the skin of your abdomen, your bone marrow, or your affected organ. This is then sent to the laboratory so that it can be checked for amyloidosis.

Images

Images of the organs which are affected by amyloidosis can help to establish the extent of your disease. The tests can include the following:

Echocardiogram

This technology uses sound waves which create moving images that show how well your heart is functioning. It can also show heart damage which may be specific to particular types of amyloidosis.

Magnetic resonance imaging (MRI)

MRI uses radio waves and a strong magnetic field for creating detailed images of the tissues and organs in your body. These can help your doctor assess the structure and function of your heart.

Nuclear imaging

In this test, tiny amounts of radioactive material, which are also known as tracers, are injected into a vein. This can reveal early heart damage which is caused by certain types of amyloidosis.

Treatment

There is no permanent cure yet known, for amyloidosis. But treatment can help to manage the signs and symptoms and stop or slow further production of amyloid protein. If the amyloidosis has been triggered by another condition, such as rheumatoid arthritis or tuberculosis, then treating the underlying condition may help.

Treatments generally include medications and surgery.

Chemotherapy

Many of the medicines which are used to treat some forms of cancer are used in AL amyloidosis as they might help to stop the growth of abnormal cells producing the protein leading to the formation of amyloid.

Heart medications

If your heart is affected, your doctor may suggest blood thinners to reduce the risk of clots, as well as medications, to control your heart rate. It is also important to reduce your salt intake.

Surgical and other procedures

Autologous blood stem cell transplant – In this procedure, your own cells are collected from your blood through a vein. They are stored for a short time while you receive high-dose chemotherapy. The stem cells are then returned to your body through a vein. This treatment is generally appropriate for people whose disease is not advanced and whose heart is not affected much.

Dialysis

If your kidneys have been damaged by amyloidosis, dialysis might be required. This procedure uses a machine that is able to filter wastes, salts, and fluid from your blood.

Organ transplant

Your doctor might also suggest surgery to replace your heart or kidneys if amyloid deposits have caused severe damage to those organs.

Complications

Amyloidosis can lead to serious complications in the following organs:

Heart – Amyloid reduces the ability of your heart to fill with blood between heartbeats. As less blood is pumped with each beat, this can lead you to experience shortness of breath. If amyloidosis affects the electrical system of your heart, the heart rhythm may get disturbed. Heart problems which are related to amyloid can become life-threatening.

Nervous system – You might experience pain, numbness, or tingling on your fingers. You might also experience numbness, lack of feeling, or a burning sensation in your toes or the soles of your feet. If amyloid affects the nerves controlling your bowel function, you may experience periods of alternating constipation or even diarrhea. If it affects the nerves that control blood pressure, you may feel faint if you stand up too quickly.

Kidneys – Amyloid can harm the filtering system of the kidneys, and this can cause the protein to leak from your blood into your urine. The kidneys’ ability to remove waste from the body gets lowered, which can result in kidney failure and may require dialysis.

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