Best Doctors in India for Pheochromocytoma Treatment
Best Hospitals in India for Pheochromocytoma Treatment
- City: Bengaluru, India
Hospital Highlights:
- Fortis Hospital Bannerghatta, Bengaluru was established in 2006.
- The hospital is a 276 bedded multi-specialty tertiary care facility.
- The hospital specializes in cutting-edge medical technology and dedicated patient care services.
- The hospital is equipped with state-of-the-art technologies like trans-radial angioplasty, trans-abdominal cardiac surgery, and computerized TKR navigation surgery.
- The hospital provides specialty medical services in cardiology, cardiac surgery, orthopedics, neurology, neuro-surgery, GI, and Minimal Access Surgery (MAS).
- City: Chennai, India
Hospital Highlights:
- Fortis Malar was established in 1992 and was formerly known as Malar Hospital.
- The hospital specializes in cutting-edge medical technology and dedicated patient care services.
- The hospital is multi-specialty, tertiary care facility with 180 beds.
- The hospital offers comprehensive medical care in specialties such as cardiology, cardio-thoracic surgery, neurology, neurosurgery, orthopedics, nephrology, gynecology, gastroenterology, urology, pediatrics, and diabetes.
- City: New Delhi, India
Hospital Highlights:
- Established in 1996, Pushpawati Singhania Research Institute is one of the top hospitals in the NCR region, as well as one of the top facilities in India for gastroenterology. The hospital is one of South Asia’s first institutes in medical and surgical treatment for diseases related to digestion.
- The hospital is equipped with state-of-the art facilities coupled with the latest equipment as well as renowned consultants from various parts of India as well as other parts of the world.
- City: New Delhi, India
Hospital Highlights:
- State-of-the-art technology and devoted healthcare professionals have been brought together under one roof at Venkateshwar Hospital to provide genuine medical care. The hospital’s professionals work together as a team to deliver the best possible treatment to their patients, using the most sophisticated equipment and information technology.
- Venkateshwar Hospital’s mission is to attain global excellence in healthcare by employing evidence-based, ethical clinical practices and cutting-edge technology by a team of highly skilled experts.
- City: New Delhi, India
Hospital Highlights:
- Sir Ganga Ram Hospital, New Delhi is known to provide the latest medical procedures with the latest technology in all of its units.
- The hospital has a team of reputed doctors, nurses, and healthcare professionals that ensure that patients receive quality care at affordable costs.
- Staffed with a team of highly qualified doctors, dedicated nurses, and paramedical and non-medical staff, the hospital aims to lead in healthcare delivery, medical education, training, and research.
- As per the vision of the founder, the hospital also provides free treatment to the economically weaker sections of society.
- Sir Ganga Ram Hospital also provides training to young doctors under the Diplomate in National Board(DNB) program. The DNB program at the hospital was started in 1984 and it is known for currently running the maximum number of DNB specialties in the country. It also has the distinction of having the first bone bank in India.
- City: Kerala, India
Hospital Highlights:
- Established in 2019, Apollo Adlux Hospital is the first Apollo Hospital in Kerala and the 73rd hospital owned by Apollo Group in India. With the state’s most advanced, comprehensive healthcare infrastructure and cutting-edge technologies, Apollo Adlux Hospital stands as an example of medical excellence in Kerala.
- With over 34 multi-specialty departments, the hospital believes in providing the best quality treatment to its patients at affordable rates, ensuring comfort at their difficult times.
- The 300-bed hospital is managed by a team of highly qualified and experienced experts who delivers exceptional hospitality to their patients and treats them with great compassion.
- With its affiliation with the Apollo Hospitals Group, the hospital aims in providing patients with top-notch healthcare services while also serving communities in Kerala.
- The hospital has good railway and road connections, and is conveniently close to Cochin International Airport.
- City: Gurugram, India
Hospital Highlights:
- Situated near DLF Cyber City, Gurugram, Narayana Superspecialty Hospital is one of the top medical facilities in the Delhi NCR region, catering to the needs of the people. Known for its commitment to quality medical care and patient service, the hospital is a state-of-the-art facility with planned and well-equipped sections, which includes a spacious OPD area as well as comfortable patient rooms.
- It is the closest super-specialty hospital from Indira Gandhi International Airport towards Gurugram, and also the nearest super specialty hospital from DLF Cyber City. It is also close to major residential areas in Gurugram.
- It is part of the renowned Narayana Health Group. Established in 2000, by Dr. Devi Shetty, a renowned cardiac surgeon, it has grown to be one fo India’s leading healthcare groups.
- City: Noida, India
Hospital Highlights:
- Fortis Hospital, Noida, stands as one of the oldest and most trusted healthcare institutions in the region, setting a benchmark for comprehensive medical care.
- As the second mega hub hospital in the Fortis Healthcare Group, Fortis Hospital, Noida, upholds a legacy of trust among more than 1.2 million patients. By integrating top-tier professionals with cutting-edge technology, the hospital delivers superior treatment across various medical disciplines.
- Specializing in advanced Neurosciences, Orthopedics, Kidney and Liver Transplant Programmes, Fortis Hospital, Noida has successfully performed over 1,500 transplants, solidifying its reputation as a leader in specialized medical interventions.
Pheochromocytoma
Pheochromocytoma is a rare type of tumor that usually grows in the adrenal glands, above the kidneys. It is also known as an adrenal paraganglioma or a chromaffin cell tumor. It is generally common in adults between the ages of 30 to 50, though people of all ages might have it. Ten percent of all cases are known to occur among children.
Your adrenal glands produce hormones for controlling things like your metabolism and your blood pressure. A pheochromocytoma releases hormones as well, at much higher levels than normal. These extra hormones can lead to high blood pressure, and this might lead to damage to several of your organs, such as your brain, heart, lungs, and kidneys.
Though most pheochromocytoma tumors are benign, around 10 to 15 percent of them are generally cancerous, and they might spread to other parts of the body.
Symptoms
People having these tumors suffer from high blood pressure all the time. For others, it can go up and down.
Most people also have at least one or more of the following symptoms:
- Constipation
- Dizziness while standing
- Pale skin
- Fast or uneven heartbeat
- Severe headache
- Nausea
- Tremors
- Shortness of breath
- Unusual sweating
- Stomach, side, or back pain
- Vomiting
- Weakness
- Anxiety attacks
- Unintended weight loss
These symptoms can occur suddenly, like an attack, multiple times during a day. For some people, they might occur only a few times a month. As the tumor grows, the attacks can get stronger and might occur more often.
In some people, the attacks might be triggered by certain things such as:
- Pressure on the tumor
- Massage
- Certain medications
- Physical activity
- Childbirth
- Surgery
- Too much emotional stress
- Foods containing excessive amino acid tyramine, such as red wine, chocolate, or cheese
Causes & risk factors
Researchers are still unsure of what exactly is the cause of pheochromocytoma. This tumor develops in specialized cells, which are termed chromaffin cells, located in the center of an adrenal gland.
These cells release certain hormones, primarily adrenaline, and noradrenaline that helps to control several body functions, such as heart rate, blood pressure as well as blood sugar.
Adrenaline and noradrenaline trigger your body’s fight-or-flight response when a threat is perceived. The hormones can cause your blood pressure to increase as well as your heart to beat faster. They also prepare other body systems in order to help enable you to react quicker. A pheochromocytoma causes more of these hormones to be released even when you’re not in a threatening situation.
People having certain rare inherited disorders are at an increased risk of pheochromocytoma or paraganglioma. It is also likely that tumors associated with these disorders will be cancerous.
These genetic conditions include the following:
Multiple endocrine neoplasias, type 2 (MEN 2) – This disorder results in tumors in more than a single part of the body’s hormone-producing (endocrine) system. Other tumors which are associated with this condition may appear on the thyroid, tongue, parathyroid, lips, as well as the gastrointestinal tract.
Neurofibromatosis 1 (NF1) – This can result in multiple tumors in the skin, pigmented skin spots as well as tumors of the optic nerve.
Von Hippel-Lindau disease – This disorder can result in tumors at multiple sites, which can include the central nervous system, endocrine system, pancreas as well as kidneys.
Hereditary paraganglioma syndromes – These are inherited disorders which may result in paragangliomas or pheochromocytomas.
Diagnosis
Your doctor might require multiple tests for diagnosing this condition. These can include the following:
- PET imaging
- MRI
- Blood plasma test for catecholamine and metanephrine levels
- Laboratory tests in order to assess the hormone levels
- Urine metanephrines test for catecholamine and metanephrine levels
Treatment
Generally, the primary treatment for pheochromocytoma is surgery for removing the tumor. However, before you go for surgery, your doctor should likely recommend certain blood pressure medications. These are meant to block the actions of the high-adrenaline hormones and to lower the risk of developing extreme high blood pressure.
You will likely receive few drugs which can include alpha-blockers, for improving blood flow and decreasing blood pressure and beta-blockers, to make your heart beat slowly with less force.
It is also likely that your healthcare team will instruct you to consume a high-salt diet. These medications can cause a huge drop in your blood pressure; a high-salt diet will help you draw more fluid inside the blood vessels, and prevent you from having low blood pressure during and after the surgery.
Surgery
During the surgery, in most cases, the surgeon removes the entire adrenal gland with a pheochromocytoma using minimally invasive surgery. For this, your surgeon will need to create a few tiny openings through which he/she will insert wandlike devices equipped with video cameras and small tools.
The remaining healthy adrenal gland is able to carry out the functions normally performed by two. Blood pressure will likely return to normal within a short time.
If the other adrenal gland has been removed, then during the surgery, your doctor will remove only the tumor, and spare some of the healthy tissue.
If a tumor is cancerous, the tumor and other cancerous tissues are going to be removed. However, even if all of the cancerous tissues are not removed, surgery might limit the production of hormones. It also helps in providing some control over the blood pressure.
Cancerous pheochromocytoma treatments
Certains pheochromocytomas are also cancerous. And therefore, other treatments can be required for them, such as:
MIBG
This is a special kind of radiation therapy. It combines MIBG, a compound that attaches to the adrenal tumors, with a type of radioactive iodine. The goal of the treatment is to deliver radiation therapy to a specific site and eliminate the cancerous cells.
Chemotherapy
Chemotherapy involves using powerful drugs for killing fast-growing cancer cells.
Radiation therapy
This treatment might be used for symptomatic treatment of tumors that have spread to other parts of the body and causing pain.
Targeted cancer therapies
These medications help to stop the function of naturally occurring molecules that promote the growth and spread of cancerous cells.
Peptide receptor radionuclide therapy (PRRT)
PRRT combines a drug that targets cancer cells with a small amount of a radioactive substance. It allows radiation to be delivered to the cancer cells directly.
People having pheochromocytoma which is not cancerous generally have a 5-year survival rate of 96 percent, while for people with a cancerous tumor, the survival rate is 44 percent.
For ensuring successful treatment, an early diagnosis is not always enough. It is best that you seek out a surgeon who is highly skilled and experienced.
Complications
High blood pressure caused by the tumors can cause damage to various organs, especially tissues of the cardiovascular system, brain, or even the kidneys. Some of the critical conditions include the following:
- Heart disease
- Kidney failure
- Problems with the nerves of the eye
- Stroke